Resolving bile reflux by lanreotide in patients with Roux-en-Y gastrojejunostomy
Journal | Volume 77 - 2014 |
Issue | Fasc.4 - Case reports |
Author(s) | K. Moubax, F. Mana, D. Urbain |
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UZ Brussel, VUB (Vrije Universiteit Brussel), België. |
Reflux into the esophagus after partial or total gastrectomy is a well known problem. Even a Roux-en-Y reconstruction is not always a definitive solution. Bile reflux might occur and cause disabling symptoms, unresponsive to the classic anti-acid or anti- reflux therapy. Endoscopy and a Tc-99m-BrIDA hepatobiliary (HIDA) scan can be used to make the diagnosis. Clinical studies have shown that lanreotide (somatuline), which strongly inhibits many gastro-intestinal hormones, reduces the bile salts outputs. We present a case of a patient with bile reflux after Roux-en-Y. After administration of lanreotide he had a good clinical improve- ment and mucosal healing on endoscopy. Lanreotide can be a good treatment option for bile reflux when classic treatment fails, but clinical trials with more patients will have to confirm this. (Acta gastroenterol. belg., 2014, 77, 377-378). |
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